Potency over the unsubstituted analogues

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{"type":"standard","title":"Biharnagybajom","displaytitle":"Biharnagybajom","namespace":{"id":0,"text":""},"wikibase_item":"Q794837","titles":{"canonical":"Biharnagybajom","normalized":"Biharnagybajom","display":"Biharnagybajom"},"pageid":7998692,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/a/af/HajduBiharCounty.gif","width":301,"height":198},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/a/af/HajduBiharCounty.gif","width":301,"height":198},"lang":"en","dir":"ltr","revision":"1238733856","tid":"0df61819-5322-11ef-90d1-ca8a328be286","timestamp":"2024-08-05T11:58:40Z","description":"Place in Hajdú-Bihar, Hungary","description_source":"local","coordinates":{"lat":47.21666667,"lon":21.23333333},"content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Biharnagybajom","revisions":"https://en.wikipedia.org/wiki/Biharnagybajom?action=history","edit":"https://en.wikipedia.org/wiki/Biharnagybajom?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Biharnagybajom"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Biharnagybajom","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Biharnagybajom","edit":"https://en.m.wikipedia.org/wiki/Biharnagybajom?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Biharnagybajom"}},"extract":"Biharnagybajom is a village in Hajdú-Bihar county, in the Northern Great Plain region of eastern Hungary. It has a population of 3100 people (2001) and was built on a flood plain.","extract_html":"

Biharnagybajom is a village in Hajdú-Bihar county, in the Northern Great Plain region of eastern Hungary. It has a population of 3100 people (2001) and was built on a flood plain.

"}

{"type":"standard","title":"ADB-5'Br-PINACA","displaytitle":"ADB-5'Br-PINACA","namespace":{"id":0,"text":""},"wikibase_item":"Q120466567","titles":{"canonical":"ADB-5'Br-PINACA","normalized":"ADB-5'Br-PINACA","display":"ADB-5'Br-PINACA"},"pageid":74109941,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/2/2d/ADB-5%27Br-PINACA_structure.png/330px-ADB-5%27Br-PINACA_structure.png","width":320,"height":328},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/2/2d/ADB-5%27Br-PINACA_structure.png","width":754,"height":772},"lang":"en","dir":"ltr","revision":"1256118612","tid":"c662ac4d-9dae-11ef-8594-cd345e034a49","timestamp":"2024-11-08T08:52:25Z","description":"Synthetic cannabinoid, designer drug","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/ADB-5'Br-PINACA","revisions":"https://en.wikipedia.org/wiki/ADB-5'Br-PINACA?action=history","edit":"https://en.wikipedia.org/wiki/ADB-5'Br-PINACA?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:ADB-5'Br-PINACA"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/ADB-5'Br-PINACA","revisions":"https://en.m.wikipedia.org/wiki/Special:History/ADB-5'Br-PINACA","edit":"https://en.m.wikipedia.org/wiki/ADB-5'Br-PINACA?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:ADB-5'Br-PINACA"}},"extract":"ADB-5'Br-PINACA (5'-Br-ADB-PINACA) is an indazole-3-carboxamide based synthetic cannabinoid receptor agonist that has been sold as a designer drug. It was first identified in Abu Dhabi in September 2022 but has subsequently been found in the US and Europe. While formal pharmacology studies have not yet been carried out, ADB-5'Br-PINACA is believed to be a highly potent synthetic cannabinoid with similar potency to compounds such as MDMB-FUBINACA and 5F-ADB, which have been responsible for numerous fatal and non-fatal drug overdoses, consistent with previously reported compounds from the patent literature showing bromination of the indazole ring at the 5-, 6-, or 7- positions to increase potency over the unsubstituted analogues. ADB-5'Br-PINACA is the 5'-bromo analog of ADB-PINACA.","extract_html":"

ADB-5'Br-PINACA (5'-Br-ADB-PINACA) is an indazole-3-carboxamide based synthetic cannabinoid receptor agonist that has been sold as a designer drug. It was first identified in Abu Dhabi in September 2022 but has subsequently been found in the US and Europe. While formal pharmacology studies have not yet been carried out, ADB-5'Br-PINACA is believed to be a highly potent synthetic cannabinoid with similar potency to compounds such as MDMB-FUBINACA and 5F-ADB, which have been responsible for numerous fatal and non-fatal drug overdoses, consistent with previously reported compounds from the patent literature showing bromination of the indazole ring at the 5-, 6-, or 7- positions to increase potency over the unsubstituted analogues. ADB-5'Br-PINACA is the 5'-bromo analog of ADB-PINACA.

"}

{"type":"standard","title":"Planotortrix","displaytitle":"Planotortrix","namespace":{"id":0,"text":""},"wikibase_item":"Q7201444","titles":{"canonical":"Planotortrix","normalized":"Planotortrix","display":"Planotortrix"},"pageid":25900423,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Planotortrix_notophaea_%28Turner%2C_1926%29_%28AM_AMNZ21755-1%29.jpg/330px-Planotortrix_notophaea_%28Turner%2C_1926%29_%28AM_AMNZ21755-1%29.jpg","width":320,"height":228},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/7/77/Planotortrix_notophaea_%28Turner%2C_1926%29_%28AM_AMNZ21755-1%29.jpg","width":3579,"height":2551},"lang":"en","dir":"ltr","revision":"1106523969","tid":"4395e726-241a-11ed-8915-656c42a99042","timestamp":"2022-08-25T02:04:34Z","description":"Genus of tortrix moths","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Planotortrix","revisions":"https://en.wikipedia.org/wiki/Planotortrix?action=history","edit":"https://en.wikipedia.org/wiki/Planotortrix?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Planotortrix"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Planotortrix","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Planotortrix","edit":"https://en.m.wikipedia.org/wiki/Planotortrix?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Planotortrix"}},"extract":"Planotortrix is a genus of moths belonging to the subfamily Tortricinae of the family Tortricidae.","extract_html":"

Planotortrix is a genus of moths belonging to the subfamily Tortricinae of the family Tortricidae.

"}

{"fact":"In 1888, more than 300,000 mummified cats were found an Egyptian cemetery. They were stripped of their wrappings and carted off to be used by farmers in England and the U.S. for fertilizer.","length":189}

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